Fermi acceleration along the orbit of {\eta} Carinae

The {\eta} Carinae binary system hosts the most massive stars with the highest known mass-loss rate. Its dense wind encounters the faster wind expelled by the companion, dissipating mechanical energy in the shock, accelerating particles up to relativistic energies and producing high-energy (HE) {\gamma}-rays. We used the first 7-year data of the Fermi LAT which span two passages of {\eta} Carinae at periastron. We extracted low and HE light curves and spectra in different orbital phase bins using the new PASS8 pipeline. We used particle acceleration in hydrodynamic simulations of the system in a multi-cell geometry and compared the prediction with the observations. The {\gamma}-ray emission location is compatible with {\eta} Carinae. Two emission components are distinguished. The low-energy (LE) one cuts off below 10 GeV and its flux, modulated by the orbital motion, varies by a factor < 2. Short-term variability occurs at periastron. The HE component flux varies by a factor 3-4 but differently during the two periastrons. The variabilities observed at LE and HE during the first half of the observations, match the prediction of the simulation, assuming a surface magnetic field of 500 G. The HE component and the thermal X-ray emission were weaker than expected around the second periastron suggesting a modification of the wind density in the inner wind collision region (WCR). Diffuse shock acceleration in the WCR provides a convincing match to the observations and new diagnostic tools to probe the geometry and energetics of the system. Further observations are required to explain the periastron-to-periastron HE variability and to associate it firmly with hadronic origin. {\eta} Carinae is a pevatron at periastron. Its $\nu$ flux can be detected by IceCube after many years of observations. Orbital modulations of the HE component can be distinguished from those of photo absorption by CTA.Comment: 11 pages, 8 figure

HESS J1632-478: An energetic relic

HESS J1632-478 is an extended and still unidentified TeV source in the galactic plane. In order to identify the source of the very high energy emission and to constrain its spectral energy distribution, we used a deep observation of the field obtained with XMM-Newton together with data from Molonglo, Spitzer and Fermi to detect counterparts at other wavelengths. The spectral energy density features two large prominent bumps with the synchrotron emission peaking in the ultraviolet and the external inverse Compton emission peaking in the TeV. HESS J1632-478 is an energetic pulsar wind nebula with an age of the order of 104 years. Its bolometric (mostly GeV-TeV) luminosity reaches 10% of the current pulsar spin down power. The synchrotron nebula has a size of 1 pc and contains an unresolved point-like X-ray source, probably the pulsar with its wind termination shock

Neuroendocrine Alterations in Obese Patients with Sleep Apnea Syndrome

Obstructive sleep apnea syndrome (OSAS) is a serious, prevalent condition that has significant morbidity and mortality when untreated. It is strongly associated with obesity and is characterized by changes in the serum levels or secretory patterns of several hormones. Obese patients with OSAS show a reduction of both spontaneous and stimulated growth hormone (GH) secretion coupled to reduced insulin-like growth factor-I (IGF-I) concentrations and impaired peripheral sensitivity to GH. Hypoxemia and chronic sleep fragmentation could affect the sleep-entrained prolactin (PRL) rhythm. A disrupted Hypothalamus-Pituitary-Adrenal (HPA) axis activity has been described in OSAS. Some derangement in Thyroid-Stimulating Hormone (TSH) secretion has been demonstrated by some authors, whereas a normal thyroid activity has been described by others. Changes of gonadal axis are common in patients with OSAS, who frequently show a hypogonadotropic hypogonadism. Altogether, hormonal abnormalities may be considered as adaptive changes which indicate how a local upper airway dysfunction induces systemic consequences. The understanding of the complex interactions between hormones and OSAS may allow a multi-disciplinary approach to obese patients with this disturbance and lead to an effective management that improves quality of life and prevents associated morbidity or death

First Study of Combined Blazar Light Curves with FACT and HAWC

For studying variable sources like blazars, it is crucial to achieve unbiased monitoring, either with dedicated telescopes in pointing mode or survey instruments. At TeV energies, the High Altitude Water Cherenkov (HAWC) observatory monitors approximately two thirds of the sky every day. It uses the water Cherenkov technique, which provides an excellent duty cycle independent of weather and season. The First G-APD Cherenkov Telescope (FACT) monitors a small sample of sources with better sensitivity, using the imaging air Cherenkov technique. Thanks to its camera with silicon-based photosensors, FACT features an excellent detector performance and stability and extends its observations to times with strong moonlight, increasing the duty cycle compared to other imaging air Cherenkov telescopes. As FACT and HAWC have overlapping energy ranges, a joint study can exploit the longer daily coverage given that the observatories' locations are offset by 5.3 hours. Furthermore, the better sensitivity of FACT adds a finer resolution of features on hour-long time scales, while the continuous duty cycle of HAWC ensures evenly sampled long-term coverage. Thus, the two instruments complement each other to provide a more complete picture of blazar variability. In this presentation, the first joint study of light curves from the two instruments will be shown, correlating long-term measurements with daily sampling between air and water Cherenkov telescopes. The presented results focus on the study of the variability of the bright blazars Mrk 421 and Mrk 501 during the last two years featuring various flaring activities.Comment: 6 pages, 2 figures. Contribution to the 6th International Symposium on High Energy Gamma-Ray Astronomy (Gamma2016), Heidelberg, Germany. To be published in the AIP Conference Proceeding

The relentless variability of Mrk 421 from the TeV to the radio

The origin of the gamma-ray emission of the blazar Mrk 421 is still a matter of debate. We used 5.5 years of unbiased observing campaign data, obtained using the FACT telescope and the Fermi LAT detector at TeV and GeV energies, the longest and densest so far, together with contemporaneous multi-wavelength observations, to characterise the variability of Mrk 421 and to constrain the underlying physical mechanisms. We studied and correlated light curves obtained by ten different instruments and found two significant results. The TeV and X-ray light curves are very well correlated with a lag of <0.6 days. The GeV and radio (15 Ghz band) light curves are widely and strongly correlated. Variations of the GeV light curve lead those in the radio. Lepto-hadronic and purely hadronic models in the frame of shock acceleration predict proton acceleration or cooling timescales that are ruled out by the short variability timescales and delays observed in Mrk 421. Instead the observations match the predictions of leptonic models.Comment: 10 pages, 8 figures, 1 tabl